1892 oxygen therapy noteworthy by absence
First edition of Osler's comprehensive textbook of medicine.
Clearly from brief mentions Osler was aware of oxygen therapy.

The principles and practice of medicine
By William Osler, M.D..
New York.
D. Appleton & Company.

P. 305:
Diabetes Mellitus.
Coma is an almost hopeless complication.
Inhalations of oxygen have been recommended.
Lately intravenous injections of a saline solution as practised by Hilton Fagge.

P. 501:
Asthma.
Use of compressed air in pneumatic cabinet is beneficial.
Oxygen inhalations may also be tried.

P. 549:
Emphysema.
Inhalation of oxygen may be used.
Remedies given already mentioned in connection with bronchitis.

P. 696:
Anemia.
Dilute hydrochloric acid.
Manganese, phosphorus & oxygen recommended.

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