Marx RE. Prevention of osteoradionecrosis: A randomized prospective clinical trial of hyperbaric oxygen versus penicillin
Auteur(s)
Marx RE, Johnson RP, Kline SN.
Jaartal
1985
Tijdschrift
J Am Dent Assoc 1985;(III):49-54
Type publicatie
Onderzoek
Onderzoek
randomized prospective clinical trial
Aantal
onbekend
Selectiecriteria
onbekend
Methode
A prospective randomized trial comparing hyperbaric oxygen and systemic antibiotics in the prevention of osteoradionecrosis was presented.
Resultaat
The results indicated, in a high-risk population who required tooth removal in irradiated mandibles, that up-front hyperbaric oxygen produced an incidence of osteoradionecrosis of 5.4% as compared with the antibiotic group of 29.9% (P = .005).
Conclusie
Hyperbaric oxygen should be considered a prophylactic measure when post-irradiation dental care involving trauma to tissue is necessary.
Externe link
Indicatie
